Airway hyperreactivity: is it really important for asthma
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Airway hyperreactivity: is it really important for asthma conferencedocumentation : Royal College of Physicians, London, 1990.

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Published by IBC Technical Services in London .
Written in English


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Edition Notes

ContributionsIBC Technical Services.
ID Numbers
Open LibraryOL14306540M

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COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.   Asthma is a chronic lung disease characterized by persistent inflammation in association with airway hyperreactivity (AHR) and tissue remodeling is considered the 14 th most important Cited by: 2. The Current State of Asthma Management. In , asthma is too often viewed as a monolithic entity. Thus, when the diagnosis of “asthma” is made it is viewed as appropriate to turn towards any of several guidelines, such as those published by the National Asthma Education and Prevention Program 1, and initiate treatment based largely on the patient’s degree of severity or control. A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the : Peter J Barnes.

Publisher Summary. This chapter examines the definitions, similarities and differences between asthma and chronic obstructive pulmonary disease (COPD), drawing heavily on the latest information on asthma and COPD that is included in the guidelines on the diagnosis and management of these diseases from two widely respected global initiatives, the Global Initiative for Asthma (GINA) and the. Introduction. Obesity is an important risk factor for being diagnosed with asthma 1, has been an alarming increase in the prevalence of obesity, and in the United States it is estimated that approximately , obese people are being newly diagnosed with asthma each year r compounding the impact of obesity on asthma is the fact that obese asthmatics are difficult to treat.   Airway hyperreactivity (AHR) is a characteristic feature of bronchial asthma, and methacholine challenge testing (MCT) is well established to quantitate AHR in patients with unexplained symptoms such as cough, chest tightness and/or dyspnea, when the diagnosis of asthma is uncertain [1–10].Compared to control subjects the provoked bronchial obstruction appears earlier and at lower. Histamine airway hyper-responsiveness and mortality from chronic obstructive pulmonary disease: a cohort study J J Hospers, D S Postma, B Rijcken, S T Weiss, J P Schouten Background: Smoking and airway lability, which is expressed by histamine airway hyperresponsiveness, are known risk factors for development of respiratory symptoms. Smoking is also associated with increased mortality risks.

Abstract: Asthma is a chronic airway disorder principally characterized by bronchial hyperreactivity and airflow obstruction. Increased epithelial and smooth muscle thickness, goblet cell hyperplasia, increased mucus secretion, abnormal deposition of extracellular matrix (ECM) components in the basement membrane (BM) layer and angiogenesis are all events which occur in asthma and are defined. Introduction. Allergic asthma is a heterogeneous disease characterized by airway hyperreactivity (AHR), inflammation, goblet cell metaplasia, and increases in Th2 cytokines and IgE,,,.Although current therapies such as glucocorticoids and bronchodilators are effective in suppressing symptoms in some patients, not all asthmatic patients respond to these therapies. Airway inflammation and remodelling. Asthma is an inflammatory disorder of the airways, characterised by infiltration of mast cells, eosinophils and T-helper cell type 2 (Th2) CD4 + T-lymphocytes in the airway wall [].Eosinophils within the airways of asthmatics: 1) are recruited via a chemical gradient due to the release of chemotactic agents (interleukin (IL)-5 and eotaxin), 2) show a. In the first part of this review the important role played by the bronchial hyperreactivity caused by chronic bronchopulmonary inflammation in asthma is described. Deliberately, more emphasis is placed on the role of pro-inflammatory eosinophils, alveolar macrophages, lymphocytes and platelets rather than on mast cells and neutrophils or the numerous mediators.